Cell Culture Media, Supplements, and Reagents
Medchemexpress LLC Poly (I:C): kanamycin (1:1) sodium | 5 MG
Poly (I:C):Kanamycin (1:1) (sodium) is a 1:1 isometric complex of the synthetic double-stranded RNA analog polyinosinic-polycytidylic acid and kanamycin (sodium). The complex functions as a TLR3 and RIG-I/MDA5 agonist to activate innate and adaptive immune responses and is used as an immunostimulant and vaccine adjuvant in research. Recommended storage: -20°C; in solvent, -80°C up to 6 months or -20°C up to 1 month.
- Acts as TLR3 and RIG-I/MDA5 agonist
- Used as immunostimulant and vaccine adjuvant in research
- Includes kanamycin component with antibacterial activity
- Provided as a sodium salt complex for stability
- Store sealed at -20°C; in solvent store at -80°C (6 months) or -20°C (1 month)
Medchemexpress LLC Hygromycin A | 6379-56-2 | 511.48 | 25 MG
Hygromycin A is a *Borrelia burgdorferi*-selective antibiotic that is also a spirochete-specific antibacterial. It contributes to gut health and is utilized in Lyme disease research. In vivo, Hygromycin A selectively eliminates *Borrelia burgdorferi* and positively influences gut microbiota composition, promoting eubiosis.
- Selective antibiotic for *Borrelia burgdorferi*
- Spirochete-specific antibacterial
- Contributes to gut health
- Used for Lyme disease research
- Promotes eubiosis by impacting gut microbiota
Medchemexpress LLC Relebactam | 1174018-99-5 | 348.38 | 5 MG
Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. It also demonstrates antibacterial activity.
- Diazabicyclooctane inhibitor
- Active against wide spectrum of β-lactamases
- Shows antibacterial activity
- Used in infection research
Medchemexpress LLC Kanamycin sulfate | 25389-94-0 | 99.9% | 582.58 | 25 G
Kanamycin sulfate is an orally active broad-spectrum antibacterial agent that inhibits translocation and causes misencoding by binding to the 70S ribosomal subunit. It shows good inhibitory activity against both gram-negative and gram-positive bacteria, including M. tuberculosis and K. pneumonia.
- Effective against gram-negative and gram-positive bacteria.
- Inhibits translocation by binding to the 70S ribosomal subunit.
- Shows good inhibitory activity against sensitive and drug-resistant M. tuberculosis.
- Exhibits good inhibitory activity against K. pneumonia.
- Suitable for studies on tuberculosis and pneumonia.
- Demonstrates in vitro activity against various mycobacteria strains (MICs of 1-5 μg/mL).
- In vivo, inhibits growth of bovine tubercle bacilli in mice.
- In vivo, inhibits multiplication of K. pneumonia DT-S in mice, increasing survival rate.
Amsbio LLC MAPTrix HyGel™-V, Vitronectin Hydrogel Kit, FRHRNRKGY
MAPTrix HyGel™-V Vitronectin Hydrogel Kit FRHRNRKGY
Amsbio LLC Skeletal Muscle Cell Differentiation Medium| 500ml
Skeletal Muscle Cell Differentiation Medium 500ml for myoblast into myocytes. Componenets: DMEM (1g/L D-glucose), Horse serum, Bovine Serum Albumin, Fetuin, Penicillin , Streptomycin, Amphotericin B.
Medchemexpress LLC SCD1 inhibitor-1 | 1069094-65-0 | 99.9% | 451.54 | 10 MG
SCD1 inhibitor-1 (Compound 48) is an orally active and liver-selective inhibitor of stearoyl-CoA desaturase 1 (SCD1) with an IC50 of 8.8 nM for recombinant human SCD1 enzyme. SCD1 inhibitor-1 can be used in the study of diseases such as diabetes, hepatic steatosis and obesity.
- Orally active and liver-selective inhibitor of stearoyl-CoA desaturase 1 (SCD1).
- IC50 of 8.8 nM for recombinant human SCD1 enzyme.
- Improved effect in high-fat mice models (3-10 mg/kg; oral administration; 43 days), showing improved glucose tolerance in a dose-dependent manner and decreased body weight.
- Improved effect in high-sucrose rat models (1-10 mg/kg; oral administration; single dose), inhibiting SCD1 inhibitory activity in a dose-dependent manner in epididymal adipose tissue and the liver 6 hours after oral administration.
- Selective tissue distribution of liver/eyelid.
eMolecules 6112-76-1 | Medchem Express | 6-Mercaptopurine hydrate | 50mg | 446263309 | HY-13677A | MFCD03854445 | 170.19 | C5H6N4OS
Medchem Express | 6-Mercaptopurine hydrate | 50mg | 446263309 | HY-13677A | 6112-76-1 | MFCD03854445 | 170.190 | C5H6N4OS
eMolecules 252025-52-8 | Medchem Express | Adjudin | 5mg | 446269636 | HY-18996 | MFCD06198883 | 335.19 | C15H12Cl2N4O
Ambeed | 4-(4-Ethylpiperazin-1-ylmethyl)phenylamine | 1g | 525058421 | A147237 | 611225-86-6 | MFCD05237186 | 219.332 | C13H21N3
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eMolecules 488832-69-5 | Medchem Express | Elesclomol | 5mg | 446260597 | HY-12040 | MFCD12911784 | 400.52 | C19H20N4O2S2
Medchem Express | G-5555 (hydrochloride) | 5mg | 446270050 | HY-19635A | | MFCD31382185 | 529.420 | C25H26Cl2N6O3
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eMolecules 500-92-5 | Medchem Express | Proguanil | 10mg | 446273348 | HY-B0806 | MFCD00866201 | 253.73 | C11H16ClN5
Medchem Express | Proguanil | 10mg | 446273348 | HY-B0806 | 500-92-5 | MFCD00866201 | 253.730 | C11H16ClN5
Cell Signaling Technology Chemical Modulator, SB431542, Lyophilized, >98% Purity, 1 mg
SB431542 is a potent and selective ATP-competitive inhibitor of transforming growth factor β1 (TGF-β1) activin receptor-like kinases (ALK)-4, -5, and -7. It functions by inhibiting Smad2 signaling induced by TGF-β and activin without affecting BMP-induced Smad1 activation.
- Inhibits ALK4 and ALK5 with IC50 values of 140 nM and 94 nM, respectively, with slightly less potency against ALK7.
- Displays 100-fold greater selectivity for ALK5 compared to 25 other kinases, including p38 MAPK and JNK1.
- Enhances the proliferation and integrity of ESC-derived endothelial cells.
- Supplied as a lyophilized powder with >98% purity.
- Reconstitute 1 mg in 260.15 μL DMSO for a 10 mM stock.
eMolecules 125-65-5 | Medchem Express | Pleuromutilin | 5mg | 446275720 | HY-N2301 | 378.509 | C22H34O5
Ambeed | 6-[(tert-Butoxy)carbonyl]-6-azaspiro[2.5]octane-5-carboxylic acid | 50mg | 672839115 | A988988 | 1417743-24-8 | MFCD30802932 | 255.314 | C13H21NO4
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Apexbio Technology LLC L-Ornithine 70-26-8 500mg
L-Ornithine (CAS 70-26-8) is a non-proteinogenic amino acid integral to the urea cycle where it facilitates the conversion of excess ammonia into urea for excretion It arises from the enzymatic cleavage of urea from arginine and subsequently participates as a precursor for the biosynthesis of citrulline and arginine L-Ornithine s role in nitrogen metabolism makes it valuable for investigating pathways of ammonia detoxification amino acid synthesis and related metabolic disorders It is widely utilized in studies focused on liver function urea cycle deficiencies and the regulation of nitrogen homeostasis in cellular and animal models